category
Nature BME
date
Feb 5, 2026
slug
status
Published
summary
创新性地整合病理学基础模型与大型语言模型的嵌入表示(spEMO),通过多模态统一框架提升空间多组学数据的分析能力
tags
空间组学
type
Post

📄 原文题目

Leveraging multi-modal foundation models for analysing spatial multi-omic and histopathology data

🔗 原文链接

💡 AI 核心解读

创新性地整合病理学基础模型与大型语言模型的嵌入表示(spEMO),通过多模态统一框架提升空间多组学数据的分析能力

📝 英文原版摘要

<p>Nature Biomedical Engineering, Published online: 05 February 2026; <a href="https://www.nature.com/articles/s41551-025-01602-6">doi:10.1038/s41551-025-01602-6</a></p>Spatial multi-modal data analysis using embeddings from diverse foundation models (spEMO) represents a transformative approach that unifies embeddings from pathology foundation models with those from large language models to advance spatial multi-omics research.
欧洲山毛榉(Fagus sylvatica L.)遗传转化及CRISPR/Cas12a介导基因编辑的首次报道利用RNA引导的桥接重组酶在人类细胞中进行可编程基因组编辑
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