category
PNAS
date
Feb 18, 2026
slug
status
Published
summary
首次揭示T-钙黏蛋白通过抑制ERK信号通路发挥器官保护作用，为代谢性疾病治疗提供新靶点。
tags
基因编辑
type
Post
📄 原文题目
T-cadherin, a major adiponectin binding partner, suppresses ERK signaling in metabolic tissues
🔗 原文链接
💡 AI 核心解读
首次揭示T-钙黏蛋白通过抑制ERK信号通路发挥器官保护作用，为代谢性疾病治疗提供新靶点。
📝 英文原版摘要
Proceedings of the National Academy of Sciences, Volume 123, Issue 8, February 2026. <br />SignificanceT-cadherin, which is a major adiponectin binding partner, exerts various organ-protective effects. We demonstrated that T-cadherin suppresses ERK signaling in both cultured cells and murine tissues. T-cadherin knockdown increased ERK ...
- 作者:NotionNext
- 链接:https://tangly1024.com/article/31348bd6-1f96-8100-bb42-c43912fd5f40
- 声明:本文采用 CC BY-NC-SA 4.0 许可协议，转载请注明出处。
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