category
Nature Protocols
date
Mar 11, 2026
slug
status
Published
summary
提出基于氨基酸序列的计算方法预测蛋白质液-液相分离和淀粉样聚集倾向,揭示蛋白质序列特征与相行为之间的关系
tags
蛋白质组学
type
Post

📄 原文题目

FuzDrop: sequence-based prediction of the propensity of proteins for liquid–liquid phase separation and aggregation

🔗 原文链接

💡 AI 核心解读

提出基于氨基酸序列的计算方法预测蛋白质液-液相分离和淀粉样聚集倾向,揭示蛋白质序列特征与相行为之间的关系

📝 英文原版摘要

<p>Nature Protocols, Published online: 11 March 2026; <a href="https://www.nature.com/articles/s41596-025-01267-0">doi:10.1038/s41596-025-01267-0</a></p>FuzDrop predicts the condensation propensity of proteins on the basis of their amino acid sequences. This protocol describes the underlying theory and how to use the results to understand liquid-liquid phase separation and amyloid aggregate formation.
将磁荧光蛋白带入细胞酵母磷酸果糖激酶β亚基具有RNA解旋活性并调控细胞周期进程
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