category
PNAS
date
Mar 2, 2026
slug
status
Published
summary
发现Pri微肽通过充当细胞内在计时器,精确调控细胞命运诱导过程的短暂阶段,揭示了微肽在细胞命运决定中的动态调控机制。
tags
蛋白质组学
type
Post

📄 原文题目

Pri micropeptide functions as a cell-intrinsic timer controlling the transient phase of cell fate induction

🔗 原文链接

💡 AI 核心解读

发现Pri微肽通过充当细胞内在计时器,精确调控细胞命运诱导过程的短暂阶段,揭示了微肽在细胞命运决定中的动态调控机制。

📝 英文原版摘要

Proceedings of the National Academy of Sciences, Volume 123, Issue 10, March 2026. <br />SignificanceA large portion of the genome is transcribed into noncoding RNAs, some of which are actually translated into micropeptides from small open reading frames (sORFs). Numerous sORF-encoded micropeptides have been identified, but their functions ...
核糖核酸酶P与核糖体的协同进化利用基于AI的条件转移聚类揭示蛋白质折叠中的隐藏中间态
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