category
PNAS
date
Mar 9, 2026
slug
status
Published
summary
揭示PER2蛋白通过寡聚化实现生物钟周期动态调控的新机制，阐明磷酸化降解域对PER2稳定性的调控作用
tags
蛋白质组学
type
Post
📄 原文题目
Oligomerization of PER2 as a dynamic mode of regulation of the mammalian circadian clock
🔗 原文链接
💡 AI 核心解读
揭示PER2蛋白通过寡聚化实现生物钟周期动态调控的新机制，阐明磷酸化降解域对PER2稳定性的调控作用
📝 英文原版摘要
Proceedings of the National Academy of Sciences, Volume 123, Issue 11, March 2026. <br />SignificanceThe abundance and lifetime of the transcriptional repressor Period2 (PER2) are key determinants of the circadian time period in mammals. Phosphorylation of PER2 at the phosphodegron reduces the stability of PER2, although this phosphodegron is ...
- 作者:NotionNext
- 链接:https://tangly1024.com/article/32948bd6-1f96-8124-b605-ef9a92d1c4c9
- 声明:本文采用 CC BY-NC-SA 4.0 许可协议，转载请注明出处。
相关文章