category
PNAS
date
Feb 2, 2026
slug
status
Published
summary
发现GLOD4蛋白能够特异性地催化过氧亚硝酸盐介导的蛋白质硝化,揭示了蛋白质损伤的非随机性机制
tags
蛋白质组学
核酸蛋白工具酶
type
Post

📄 原文题目

Selective peroxynitrite-mediated protein nitration catalyzed by glyoxalase domain containing protein 4

🔗 原文链接

💡 AI 核心解读

发现GLOD4蛋白能够特异性地催化过氧亚硝酸盐介导的蛋白质硝化,揭示了蛋白质损伤的非随机性机制

📝 英文原版摘要

Proceedings of the National Academy of Sciences, Volume 123, Issue 6, February 2026. <br />SignificanceScientists have long thought that damage to proteins by the chemical peroxynitrite was random. This damage is called nitration. However, this study found that a specific protein, GLOD4, can intentionally modify other proteins using ...
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