category
Nature Communications
date
Mar 3, 2026
slug
status
Published
summary
开发长读长DNA测序技术，揭示染色体重排由微同源介导的断裂诱导复制机制在有丝分裂中产生
tags
测序技术
type
Post
📄 原文题目
Mitotic microhomology-mediated break-induced replication promotes chromoanasynthesis
🔗 原文链接
💡 AI 核心解读
开发长读长DNA测序技术，揭示染色体重排由微同源介导的断裂诱导复制机制在有丝分裂中产生
📝 英文原版摘要
<p>Nature Communications, Published online: 03 March 2026; <a href="https://www.nature.com/articles/s41467-026-70086-y">doi:10.1038/s41467-026-70086-y</a></p>Chromoanasynthesis is an elusive form of complex chromosomal rearrangement commonly detected in cancer and congenital disorder. Here, the authors develop a long-read DNA sequencing approach and show that chromoanasynthesis is generated by microhomology-mediated break induced replication in mitosis.
- 作者:NotionNext
- 链接:https://tangly1024.com/article/31848bd6-1f96-812c-9fd1-cec269c4cde6
- 声明:本文采用 CC BY-NC-SA 4.0 许可协议，转载请注明出处。
相关文章