category
Cell
date
Feb 16, 2026
slug
status
Published
summary
构建了跨器官和多时间点的内皮细胞基因表达比较图谱,揭示了不同胚胎器官间内皮细胞的转录组变异,并发现了调控器官特异性血管发育的新分子机制。
tags
单细胞测序
type
Post

📄 原文题目

A single-cell time-series atlas of endothelial cell embryonic development

🔗 原文链接

💡 AI 核心解读

构建了跨器官和多时间点的内皮细胞基因表达比较图谱,揭示了不同胚胎器官间内皮细胞的转录组变异,并发现了调控器官特异性血管发育的新分子机制。

📝 英文原版摘要

The STED-EC atlas enables inter-organ and multi-time-point comparisons of gene expression in endothelial cells, revealing substantial transcriptomic variations across endothelial cells from different embryonic organs and facilitating investigation of previously unknown molecular mechanisms that govern organ-specific vascular development.
CRISPR-Cas适应过程中Cas9介导的前间隔区选择的结构洞察CLIM-TIME识别T细胞治疗反应的转移性微环境调节因子
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