category
Nature
date
Feb 4, 2026
slug
status
Published
summary
通过跨物种单细胞和空间转录组学技术,发现表皮BMP信号是rete嵴形成的必要机制,揭示了毛发密度丧失和伤口愈合的分子基础
tags
单细胞测序
空间组学
测序技术
type
Post

📄 原文题目

Rete ridges form via evolutionarily distinct mechanisms in mammalian skin

🔗 原文链接

💡 AI 核心解读

通过跨物种单细胞和空间转录组学技术,发现表皮BMP信号是rete嵴形成的必要机制,揭示了毛发密度丧失和伤口愈合的分子基础

📝 英文原版摘要

<p>Nature, Published online: 04 February 2026; <a href="https://www.nature.com/articles/s41586-025-10055-5">doi:10.1038/s41586-025-10055-5</a></p>A spatial and single-cell transcriptomics study across multiple mammalian species identifies epidermal BMP signalling as a functional requirement for rete ridge formation, providing insight into mechanisms underlying hair density loss and wound healing.
蚊虫衣壳相互作用影响黄病毒传播媒介特异性少数粗线期piRNA通过切割mRNA提高精子适应性
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